Most participants will come from the world’s largest family to experience Alzheimer’s, an extended clan of 5,000 people who live in Medellín, Colombia, and remote mountain villages outside that city. Family members with a specific genetic mutation begin showing cognitive impairment around age 45, and full dementia around age 51, debilitated in their prime working years as their memories fade and the disease quickly assaults their ability to move, eat, speak and communicate.
Three hundred family members will participate in the initial trial. Those with the mutation will be years away from symptoms, some as young as 30.
“Because of this study, we do not feel as alone,” said Gladys Betancur, 39, a family member. Her mother died of Alzheimer’s, three of her siblings already have symptoms, and she had a hysterectomy because of her fears that she has the mutation and would pass it on to her children. “Sometimes we think that life is ending, but now we feel that people are trying to help us.”
Born, like other comic book characters, out of an otherwise trivial but life-changing animal bite, the Rabid Librarian seeks out strange, useless facts, raves about real and perceived injustices, and seeks to meet her greatest challenge of all--her own life.
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Thursday, May 17, 2012
And there's this...
New Drug Trial Seeks to Stop Alzheimer’s Before It Starts
Labels:
Alzheimer's,
Clinical Trials,
Colombia,
Genetics
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