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Showing posts with label Melatonin. Show all posts
Showing posts with label Melatonin. Show all posts

Saturday, August 29, 2026

Hmmm....

As someone who has been immensely helped by melatonin and takes it every night, this is a little concerning, even acknowledging the study's flaws.

Long-term melatonin use linked to 90% higher heart failure risk

UPDATE: I tried sleeping without it last night. I stayed up till 2:30 AM or so reading my book. Then I tried to go to bed. I couldn't sleep. I did not play on my phone or anything. I finally fell asleep about 4 AM. Since there is strong evidence of heart issues from chronic insomnia and disordered sleep, which I had in spades before I started taking melatonin, I'm in a sort of Catch-22. I think I should discuss this with my doctor. I don't currently have any heart problems except for such a minor murmur that only one doctor [my current PCP] has ever detected it by listening. I'd like to keep it that way. In the meantime, I'll keep taking it. I've tried the prescription drug trazodone and cannot take it; it makes my legs extremely restless, like I have pins and needles being poked in them. This works. I need an expert opinion. Maybe there's a reason melatonin is prescription-only in Britain.

UPDATE to the UPDATE: I have since spoken to a pharmacist and an APRN specialisin in sleep medicine and both agreed with my take that correlation does not equal causation and the studies have their flaws, and that, most importantly, the effects of insomnia and sleep disturbance on the heart are well-documented and detrimental, so if the melatonin is working, that is a good thing. The pharmacist did ask if I'd ever tried the lower dose, and I hadn't. She suggested I might give it a try and see if I had similar results. The sleep APRN agreed; they usually suggest doses of 3-20 mg of melatonin for women, but the lowest dose that works is the best. I found some 3 mg disintigrating cherry melatonin in a brand suggested by the pharmacist (since over the counter medications are not regulated by the FDA, there is a huge divide in how much melatonin is really in each product, and she said it was fairly good in testing), and I'll start a trial tonight. We'll see if it works. If not, I'll go back to what I have.

Friday, November 30, 2007

Interesting--and bad for my mother, who works overnight

Overnight shift to be classified as 'probable' cancer cause

My mom is a nurse who works sixteen-hour night shifts. According to several studies, higher incidences of breast and prostate cancer are found in night workers. This may be due to the disruption of the circadian rhythm, as well as the production of melatonin, a chemical produced overnight while we sleep that helps keep cancer at bay. Light impedes melatonin synthesis; on the other hand, while melatonin is available as a supplement, it's not recommended to take it for long periods because doing so may interfere with the body's natural production of it. Those who do swing shift may be at even higher risk, since the body doesn't really get to adjust to a schedule one way or the other. Insomniacs and others who do not work but may not get enough sleep may also be at risk.

Speaking of not enough sleep, I'm operating on five hours from last night and I'll have four tonight. Argh.